| Job Description | • Lead Applied Biotechnology (AB) support activities at Research Center in Bangalore, India.
• Manage multiple discovery technologies in support of drug discovery.
• Responsibilities will include building and leading teams that provide bioassays, gene cloning, protein expression, and protein purification to support in vitro compound characterization and structural biology.
• Build function alignments between AB in US and R & D in India
• Report group status and issues in India to US AB leaders on a regular basis.
• Identify work flow process gaps and provide solutions to close the gaps
• Lead the collaboration with third parties to strengthen functions in India.
• Build an effective team to support the functions of the Indian laboratories.
• Coordinate assay execution, technology transfer, and data communication between US and India.
• Actively manage project timelines and deliverables in India.
• Manage molecular biology and protein production group, guiding workflow improvements and ensuring reagent availability for assays and cDNA, mutagenesis and clone set deliverables to US.
• Working closely with the SATT leader in India.
• Monitor SATT function timeline and deliverables.
|
| Skill Required | • Ten years of experience in drug discovery in pharmaceutical companies with a PhD degree in Molecular Biology and or related areas.
• Strong working knowledge on enzyme kinetics, receptor pharmacology and or cell biology and cell line constructions.
• Familiarity with bioassay technologies that are used for studying enzymes, kinases, GPCRs, ion channel and or nuclear hormone receptors.
• Familiarity with current methods in molecular biology, recombinant protein expression, protein purification, and biochemistry, and an ability to guide and manage workflow in these areas.
• Experience in one or more of the following disease research areas oncology, metabolic diseases, cardiovascular diseases, immunology and or CNS.
• A strong publication record in drug discovery.
• Strong leadership in project and people management.
• Understanding of statistical data analysis and assay performance parameters.
• Excellent interpersonal skills, good team worker and excellent written and verbal communication skills.
• Knowledge in advanced bioassay technologies and automation platforms is plus.
• Detail oriented with outstanding coordination and organizational skills.
• Must have the ability to flexibly handle multiple projects.
• Creativity and strong problem solving skills.
• Familiarity with other drug discovery disciplines such as medicinal chemistry, metabolism, and pharmacokinetics
|
